The Mercedes-Benz 600 was launched in September 1964, and was provided in 4 completely different physique variants. Initially, there was the usual saloon with a wheelbase of three,200 millimetres, in addition to the elongated Pullman Saloon with a wheelbase of three,900 millimetres.

In 1965, particular safety variations of each these variants grew to become out there. Afterward, the lineup expanded to incorporate the Pullman Landaulet and Pullman Limousine, that includes six doorways. 

Of the overall manufacturing, a big variety of 743 Mercedes-Benz 600s have been delivered to the USA. Following that, Germany acquired 589 items, France had 151 autos, and Nice Britain possessed 126 examples. Notably, two distinctive custom-made fashions have been created: a long-wheelbase Landaulet for Pope Paul VI and a short-wheelbase Landaulet for Depend Berckheim.

An distinctive addition in 1965 was a singular two-door coupé, crafted in Sindelfingen. This creation remained one-of-a-kind and served as an exploration into the potential of a grand coupé, presumably as a successor to the 300 Sc (W 188 II).